from pharmadata import pharmaverseadam
meta = pharmaverseadam.meta('adpc')
print(f"Rows: {meta.number_rows:,} Columns: {meta.number_columns}")Rows: 4,479 Columns: 128adpc
adpc
Pharmacokinetic Concentrations
Structure: One or more records per subject per analysis parameter per analysis timepoint
Variables
Show variable specs
shape: (128, 5)
| variable | label | type | mandatory | role |
|---|---|---|---|---|
| str | str | str | str | str |
| "STUDYID" | "Study Identifier" | "String" | "Yes" | "Identifier Variables for BDS Datasets" |
| "USUBJID" | "Unique Subject Identifier" | "String" | "Yes" | "Identifier Variables for BDS Datasets" |
| "SUBJID" | "Subject Identifier for the Study" | "String" | "No" | "Identifier Variables for BDS Datasets" |
| "SITEID" | "Study Site Identifier" | "String" | "No" | "Identifier Variables for BDS Datasets" |
| "COUNTRY" | "Country" | "String" | "No" | null |
| "RFSTDTC" | "Subject Reference Start Date/Time" | "String" | "No" | null |
| "RFENDTC" | "Subject Reference End Date/Time" | "String" | "No" | null |
| "RFXSTDTC" | "Date/Time of First Study Treatment" | "String" | "No" | null |
| "RFXENDTC" | "Date/Time of Last Study Treatment" | "String" | "No" | null |
| "RFPENDTC" | "Date/Time of End of Participation" | "String" | "No" | null |
| "SCRFDT" | "Screen Failure Date" | "Date" | "No" | null |
| "FRVDT" | "Final Retrieval Visit Date" | "Date" | "No" | null |
| "DTHDTC" | "Date/Time of Death" | "String" | "No" | null |
| "DTHADY" | "Relative Day of Death" | "Float64" | "No" | null |
| "DTHFL" | "Subject Death Flag" | "String" | "No" | null |
| "LDDTHELD" | "Elapsed Days from Last Dose to Death" | "Float64" | "No" | null |
| "LDDTHGR1" | "Last Dose to Death - Days Elapsed Grp 1" | "String" | "No" | null |
| "DTH30FL" | "Under 30 Group" | "String" | "No" | null |
| "DTHA30FL" | "Over 30 Group" | "String" | "No" | null |
| "DTHDOM" | "Domain for Date of Death Collection" | "String" | "No" | null |
| "DTHB30FL" | "Over 30 plus 30 days Group" | "String" | "No" | null |
| "ASEQ" | "Analysis Sequence Number" | "Int32" | "No" | "Identifier Variables for BDS Datasets" |
| "REGION1" | "Geographic Region 1" | "String" | "No" | null |
| "DMDTC" | "Date/Time of Collection" | "String" | "No" | null |
| "DMDY" | "Study Day of Collection" | "Float64" | "No" | null |
| "AGE" | "Age" | "Float64" | "No" | "ADSL Subject Demographics Variables" |
| "AGEU" | "Age Units" | "String" | "No" | "ADSL Subject Demographics Variables" |
| "AGEGR1" | "Pooled Age Group 1" | "String" | "No" | null |
| "SEX" | "Sex" | "String" | "No" | "ADSL Subject Demographics Variables" |
| "RACE" | "Race" | "String" | "No" | "ADSL Subject Demographics Variables" |
| "RACEGR1" | "Pooled Race Group 1" | "String" | "No" | null |
| "ETHNIC" | "Ethnicity" | "String" | "No" | null |
| "SAFFL" | "Safety Population Flag" | "String" | "No" | "ADSL Population Indicator Variables" |
| "ARM" | "Description of Planned Arm" | "String" | "No" | "ADSL Treatment Variables" |
| "ARMCD" | "Planned Arm Code" | "String" | "No" | null |
| "ACTARM" | "Description of Actual Arm" | "String" | "No" | "ADSL Treatment Variables" |
| "ACTARMCD" | "Actual Arm Code" | "String" | "No" | null |
| "TRT01P" | "Planned Treatment for Period 01" | "String" | "No" | null |
| "TRT01A" | "Actual Treatment for Period 01" | "String" | "No" | null |
| "TRTSDT" | "Date of First Exposure to Treatment" | "Date" | "No" | "ADSL Treatment Timing Variables" |
| "TRTSDTM" | "Datetime of First Exposure to Treatment" | "Datetime" | "No" | "ADSL Treatment Timing Variables" |
| "TRTSTMF" | "Time of First Exposure Imput. Flag" | "String" | "No" | "ADSL Treatment Timing Variables" |
| "TRTEDT" | "Date of Last Exposure to Treatment" | "Date" | "No" | "ADSL Treatment Timing Variables" |
| "TRTEDTM" | "Datetime of Last Exposure to Treatment" | "Datetime" | "No" | "ADSL Treatment Timing Variables" |
| "TRTETMF" | "Time of Last Exposure Imput. Flag" | "String" | "No" | "ADSL Treatment Timing Variables" |
| "EOSSTT" | "End of Study Status" | "String" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "EOSDT" | "End of Study Date" | "Date" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "RFICDTC" | "Date/Time of Informed Consent" | "String" | "No" | null |
| "RANDDT" | "Date of Randomization" | "Date" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "LSTALVDT" | "Date Last Known Alive" | "Date" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "TRTDURD" | "Total Treatment Duration (Days)" | "Float64" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "DTHDT" | "Date of Death" | "Date" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "DTHDTF" | "Date of Death Imputation Flag" | "String" | "No" | "ADSL Subject-Level Trial Experience Variables" |
| "DTHCAUS" | "Cause of Death" | "String" | "No" | null |
| "DTHCGR1" | "Cause of Death Reason 1" | "String" | "No" | null |
| "DOSEP" | "Planned Treatment Dose" | "Float64" | "No" | "Record-Level Dose Variables for BDS Datasets" |
| "DOSEA" | "Actual Treatment Dose" | "Float64" | "No" | "Record-Level Dose Variables for BDS Datasets" |
| "DOSEU" | "Treatment Dose Units" | "String" | "No" | "Record-Level Dose Variables for BDS Datasets" |
| "ADT" | "Analysis Date" | "Date" | "No" | "Timing Variables for BDS Datasets" |
| "ATM" | "Analysis Time" | "Time" | "No" | "Timing Variables for BDS Datasets" |
| "ADTM" | "Analysis Datetime" | "Datetime" | "No" | "Timing Variables for BDS Datasets" |
| "ADY" | "Analysis Relative Day" | "Float64" | "No" | "Timing Variables for BDS Datasets" |
| "ATMF" | "Analysis Time Imputation Flag" | "String" | "No" | "Timing Variables for BDS Datasets" |
| "ASTDT" | "Analysis Start Date" | "Date" | "No" | "Timing Variables for BDS Datasets" |
| "ASTTM" | "Analysis Start Time" | "Time" | "No" | "Timing Variables for BDS Datasets" |
| "ASTDTM" | "Analysis Start Datetime" | "Datetime" | "No" | "Timing Variables for BDS Datasets" |
| "AENDT" | "Analysis End Date" | "Date" | "No" | "Timing Variables for BDS Datasets" |
| "AENTM" | "Analysis End Time" | "Time" | "No" | "Timing Variables for BDS Datasets" |
| "AENDTM" | "Analysis End Datetime" | "Datetime" | "No" | "Timing Variables for BDS Datasets" |
| "AVISIT" | "Analysis Visit" | "String" | "No" | "Timing Variables for BDS Datasets" |
| "AVISITN" | "Analysis Visit (N)" | "Float64" | "No" | "Timing Variables for BDS Datasets" |
| "ATPT" | "Analysis Timepoint" | "String" | "No" | "Timing Variables for BDS Datasets" |
| "ATPTN" | "Analysis Timepoint (N)" | "Float64" | "No" | "Timing Variables for BDS Datasets" |
| "ATPTREF" | "Analysis Timepoint Reference" | "String" | "No" | "Timing Variables for BDS Datasets" |
| "PARAM" | "Parameter" | "String" | "Yes" | "Analysis Parameter Variables for BDS Datasets" |
| "PARAMCD" | "Parameter Code" | "String" | "Yes" | "Analysis Parameter Variables for BDS Datasets" |
| "PARAMN" | "Parameter (N)" | "Float64" | "No" | "Analysis Parameter Variables for BDS Datasets" |
| "PARCAT1" | "Parameter Category 1" | "String" | "No" | null |
| "AVAL" | "Analysis Value" | "Float64" | "No" | "Analysis Parameter Variables for BDS Datasets" |
| "AVALU" | "Analysis Value Unit" | "String" | "No" | null |
| "AVALCAT1" | "Analysis Value Category 1" | "String" | "No" | null |
| "BASE" | "Baseline Value" | "Float64" | "No" | "Analysis Parameter Variables for BDS Datasets" |
| "BASETYPE" | "Baseline Type" | "String" | "No" | "Analysis Parameter Variables for BDS Datasets" |
| "CHG" | "Change from Baseline" | "Float64" | "No" | "Analysis Parameter Variables for BDS Datasets" |
| "DTYPE" | "Derivation Type" | "String" | "No" | "Analysis Descriptor Variables for BDS Datasets" |
| "ABLFL" | "Baseline Record Flag" | "String" | "No" | "Flag Variables for BDS Datasets" |
| "ANL01FL" | "Analysis Flag 01" | "String" | "No" | null |
| "ANL02FL" | "Analysis Flag 02" | "String" | "No" | null |
| "SRCDOM" | "Source Data" | "String" | "No" | "Datapoint Traceability Variables" |
| "SRCVAR" | "Source Variable" | "String" | "No" | "Datapoint Traceability Variables" |
| "SRCSEQ" | "Source Sequence Number" | "Float64" | "No" | "Datapoint Traceability Variables" |
| "NFRLT" | "Nom. Rel. Time from Analyte First Dose" | "Float64" | "No" | null |
| "PCTESTCD" | "Pharmacokinetic Test Short Name" | "String" | "No" | null |
| "PCTEST" | "Pharmacokinetic Test Name" | "String" | "No" | null |
| "PCORRES" | "Result or Finding in Original Units" | "String" | "No" | null |
| "PCORRESU" | "Original Units" | "String" | "No" | null |
| "PCSTRESC" | "Character Result/Finding in Std Format" | "String" | "No" | null |
| "PCSTRESN" | "Numeric Result/Finding in Standard Units" | "Float64" | "No" | null |
| "PCSTRESU" | "Standard Units" | "String" | "No" | null |
| "PCNAM" | "Vendor Name" | "String" | "No" | null |
| "PCSPEC" | "Specimen Material Type" | "String" | "No" | null |
| "PCLLOQ" | "Lower Limit of Quantitation" | "Float64" | "No" | null |
| "VISIT" | "Visit Name" | "String" | "No" | null |
| "VISITNUM" | "Visit Number" | "Float64" | "No" | null |
| "VISITDY" | "Planned Study Day of Visit" | "Float64" | "No" | null |
| "PCDTC" | "Date/Time of Specimen Collection" | "String" | "No" | null |
| "PCDY" | "Actual Study Day of Specimen Collection" | "Float64" | "No" | null |
| "PCTPT" | "Planned Time Point Name" | "String" | "No" | null |
| "PCTPTNUM" | "Planned Time Point Number" | "Float64" | "No" | null |
| "FANLDTM" | "First Datetime of Dose for Analyte" | "Datetime" | "No" | null |
| "AFRLT" | "Act. Rel. Time from Analyte First Dose" | "Float64" | "No" | null |
| "ARRLT" | "Actual Rel. Time from Ref. Dose" | "Float64" | "No" | null |
| "PCRFTDTM" | "Reference Datetime of Dose for Analyte" | "Datetime" | "No" | null |
| "FANLDT" | "First Date of Dose for Analyte" | "Date" | "No" | null |
| "FANLTM" | "First Time of Dose for Analyte" | "Time" | "No" | null |
| "PCRFTDT" | "Reference Date of Dose for Analyte" | "Date" | "No" | null |
| "PCRFTTM" | "Reference Time of Dose for Analyte" | "Time" | "No" | null |
| "NRRLT" | "Nominal Rel. Time from Ref. Dose" | "Float64" | "No" | null |
| "FRLTU" | "Rel. Time from First Dose Unit" | "String" | "No" | null |
| "RRLTU" | "Rel. Time from Ref. Dose Unit" | "String" | "No" | null |
| "ALLOQ" | "Analysis Lower Limit of Quantitation" | "Float64" | "No" | null |
| "MRRLT" | "Modified Rel. Time from Ref. Dose" | "Float64" | "No" | null |
| "HTBL" | "Numeric Result/Finding in Standard Units" | "Float64" | "No" | null |
| "HTBLU" | "Standard Units" | "String" | "No" | null |
| "WTBL" | "Numeric Result/Finding in Standard Units" | "Float64" | "No" | null |
| "WTBLU" | "Standard Units" | "String" | "No" | null |
| "BMIBL" | "Baseline Body Mass Index (kg/m2)" | "Float64" | "No" | null |
| "BMIBLU" | "BMI at Baseline (Unit)" | "String" | "No" | null |
Examples
from great_docs import tbl_explorer
from pharmadata import pharmaverseadam
tbl_explorer(pharmaverseadam.adpc.head(10))PolarsRows10Columns128 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
STUDYID str |
USUBJID str |
SUBJID str |
SITEID str |
COUNTRY str |
RFSTDTC str |
RFENDTC str |
RFXSTDTC str |
RFXENDTC str |
RFPENDTC str |
SCRFDT date |
FRVDT date |
DTHDTC str |
DTHADY f64 |
DTHFL str |
LDDTHELD f64 |
LDDTHGR1 str |
DTH30FL str |
DTHA30FL str |
DTHDOM str |
DTHB30FL str |
ASEQ i32 |
REGION1 str |
DMDTC str |
DMDY f64 |
AGE f64 |
AGEU str |
AGEGR1 str |
SEX str |
RACE str |
RACEGR1 str |
ETHNIC str |
SAFFL str |
ARM str |
ARMCD str |
ACTARM str |
ACTARMCD str |
TRT01P str |
TRT01A str |
TRTSDT date |
TRTSDTM dtime |
TRTSTMF str |
TRTEDT date |
TRTEDTM dtime |
TRTETMF str |
EOSSTT str |
EOSDT date |
RFICDTC str |
RANDDT date |
LSTALVDT date |
TRTDURD f64 |
DTHDT date |
DTHDTF str |
DTHCAUS str |
DTHCGR1 str |
DOSEP f64 |
DOSEA f64 |
DOSEU str |
ADT date |
ATM time |
ADTM dtime |
ADY f64 |
ATMF str |
ASTDT date |
ASTTM time |
ASTDTM dtime |
AENDT date |
AENTM time |
AENDTM dtime |
AVISIT str |
AVISITN f64 |
ATPT str |
ATPTN f64 |
ATPTREF str |
PARAM str |
PARAMCD str |
PARAMN f64 |
PARCAT1 str |
AVAL f64 |
AVALU str |
AVALCAT1 str |
BASE f64 |
BASETYPE str |
CHG f64 |
DTYPE str |
ABLFL str |
ANL01FL str |
ANL02FL str |
SRCDOM str |
SRCVAR str |
SRCSEQ f64 |
NFRLT f64 |
PCTESTCD str |
PCTEST str |
PCORRES str |
PCORRESU str |
PCSTRESC str |
PCSTRESN f64 |
PCSTRESU str |
PCNAM str |
PCSPEC str |
PCLLOQ f64 |
VISIT str |
VISITNUM f64 |
VISITDY f64 |
PCDTC str |
PCDY f64 |
PCTPT str |
PCTPTNUM f64 |
FANLDTM dtime |
AFRLT f64 |
ARRLT f64 |
PCRFTDTM dtime |
FANLDT date |
FANLTM time |
PCRFTDT date |
PCRFTTM time |
NRRLT f64 |
FRLTU str |
RRLTU str |
ALLOQ f64 |
MRRLT f64 |
HTBL f64 |
HTBLU str |
WTBL f64 |
WTBLU str |
BMIBL f64 |
BMIBLU str |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 1 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-18 | None | 2013-07-18 23:30:00+00:00 | -1 | None | None | None | None | None | None | None | Day 1 | 1 | Pre-dose | -0.5 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 0 | ug/ml | <BLQ | 0 | Day 1 Baseline | 0 | None | Y | Y | Y | PC | SEQ | 1 | 0 | XAN | XANOMELINE | <BLQ | ug/ml | <BLQ | 0 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-18T23:30:00 | -1 | Pre-dose | -0.5 | 2013-07-19 00:00:00+00:00 | -0.5 | -0.5 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 0 | HOURS | None | 0.01 | 0 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 1 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 2 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | 00:00:00 | 2013-07-19 00:00:00+00:00 | 1 | None | 2013-07-19 | 00:00:00 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 00:00:00+00:00 | Day 1 | 1 | Dose | 0 | Day 1 | Xanomeline Patch Dose | DOSE | 2 | None | 54 | mg | None | None | Day 1 Baseline | None | None | None | Y | Y | EX | SEQ | 1 | 0 | None | None | None | None | None | None | None | None | None | None | BASELINE | 3 | 1 | None | None | None | None | 2013-07-19 00:00:00+00:00 | 0 | 0 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 0 | None | None | None | 0 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 2 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 3 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 00:05:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 5 Min Post-dose | 0.08 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 0.101566224882 | ug/ml | 0.102 | 0 | Day 1 Baseline | 0.101566224882 | None | None | Y | Y | PC | SEQ | 2 | 0.0833333333333 | XAN | XANOMELINE | 0.101566224882241 | ug/ml | 0.101566224882241 | 0.101566224882 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T00:05:00 | 1 | 5 Min Post-dose | 0.08 | 2013-07-19 00:00:00+00:00 | 0.0833333333333 | 0.0833333333333 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 0.0833333333333 | HOURS | HOURS | 0.01 | 0.0833333333333 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 3 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 4 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 00:30:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 30 Min Post-dose | 0.5 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 0.546901773709 | ug/ml | 0.547 | 0 | Day 1 Baseline | 0.546901773709 | None | None | Y | Y | PC | SEQ | 3 | 0.5 | XAN | XANOMELINE | 0.546901773708848 | ug/ml | 0.546901773708848 | 0.546901773709 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T00:30:00 | 1 | 30 Min Post-dose | 0.5 | 2013-07-19 00:00:00+00:00 | 0.5 | 0.5 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 0.5 | HOURS | HOURS | 0.01 | 0.5 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 4 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 5 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 01:00:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 1h Post-dose | 1 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 0.925465387145 | ug/ml | 0.925 | 0 | Day 1 Baseline | 0.925465387145 | None | None | Y | Y | PC | SEQ | 4 | 1 | XAN | XANOMELINE | 0.925465387145289 | ug/ml | 0.925465387145289 | 0.925465387145 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T01:00:00 | 1 | 1h Post-dose | 1 | 2013-07-19 00:00:00+00:00 | 1 | 1 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 1 | HOURS | HOURS | 0.01 | 1 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 5 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 6 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 01:30:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 1.5h Post-dose | 1.5 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 1.18750587834 | ug/ml | 1.19 | 0 | Day 1 Baseline | 1.18750587834 | None | None | Y | Y | PC | SEQ | 5 | 1.5 | XAN | XANOMELINE | 1.18750587834024 | ug/ml | 1.18750587834024 | 1.18750587834 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T01:30:00 | 1 | 1.5h Post-dose | 1.5 | 2013-07-19 00:00:00+00:00 | 1.5 | 1.5 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 1.5 | HOURS | HOURS | 0.01 | 1.5 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 6 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 7 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 02:00:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 2h Post-dose | 2 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 1.36888944662 | ug/ml | 1.37 | 0 | Day 1 Baseline | 1.36888944662 | None | None | Y | Y | PC | SEQ | 6 | 2 | XAN | XANOMELINE | 1.36888944661923 | ug/ml | 1.36888944661923 | 1.36888944662 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T02:00:00 | 1 | 2h Post-dose | 2 | 2013-07-19 00:00:00+00:00 | 2 | 2 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 2 | HOURS | HOURS | 0.01 | 2 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 7 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 8 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 04:00:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 4h Post-dose | 4 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 1.68314757616 | ug/ml | 1.68 | 0 | Day 1 Baseline | 1.68314757616 | None | None | Y | Y | PC | SEQ | 7 | 4 | XAN | XANOMELINE | 1.68314757616444 | ug/ml | 1.68314757616444 | 1.68314757616 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T04:00:00 | 1 | 4h Post-dose | 4 | 2013-07-19 00:00:00+00:00 | 4 | 4 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 4 | HOURS | HOURS | 0.01 | 4 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 8 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 9 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 06:00:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 0-6h Post-dose | 3 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | URINE | 24.9423721085 | ug/ml | 24.9 | None | Day 1 Baseline | None | None | None | Y | Y | PC | SEQ | 15 | 3 | XAN | XANOMELINE | 24.9423721084785 | ug/ml | 24.9423721084785 | 24.9423721085 | ug/ml | Imaginary Labs | URINE | 0.01 | BASELINE | 3 | 1 | 2013-07-19T06:00:00 | 1 | 0-6h Post-dose | 3 | 2013-07-19 00:00:00+00:00 | 6 | 6 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 3 | HOURS | HOURS | 0.01 | 6 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |
| 9 | CDISCPILOT01 | 01-701-1028 | 1028 | 701 | USA | 2013-07-19 | 2014-01-14 | 2013-07-19 | 2014-01-14 | 2014-01-14T11:10 | None | None | None | None | None | None | None | None | None | None | None | 10 | NA | 2013-07-11 | -8 | 71 | YEARS | >64 | M | WHITE | White | NOT HISPANIC OR LATINO | Y | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xan_Hi | Xanomeline High Dose | Xanomeline High Dose | 2013-07-19 | 2013-07-19 00:00:00+00:00 | H | 2014-01-14 | 2014-01-14 23:59:59+00:00 | H | COMPLETED | 2014-01-14 | None | 2013-07-19 | 2014-01-14 | 180 | None | None | None | None | 81 | 54 | mg | 2013-07-19 | None | 2013-07-19 06:00:00+00:00 | 1 | None | None | None | None | None | None | None | Day 1 | 1 | 6h Post-dose | 6 | Day 1 | Pharmacokinetic concentration of Xanomeline | XAN | 1 | PLASMA | 1.75529231527 | ug/ml | 1.76 | 0 | Day 1 Baseline | 1.75529231527 | None | None | Y | Y | PC | SEQ | 8 | 6 | XAN | XANOMELINE | 1.75529231526602 | ug/ml | 1.75529231526602 | 1.75529231527 | ug/ml | Imaginary Labs | PLASMA | 0.01 | BASELINE | 3 | 1 | 2013-07-19T06:00:00 | 1 | 6h Post-dose | 6 | 2013-07-19 00:00:00+00:00 | 6 | 6 | 2013-07-19 00:00:00+00:00 | 2013-07-19 | 00:00:00 | 2013-07-19 | 00:00:00 | 6 | HOURS | HOURS | 0.01 | 6 | 177.8 | cm | 99.34 | kg | 31.4239403989 | kg/m^2 |